FDG PET/MR Imaging of Peripheral Pain Generators in Persistent Post-Surgical Pain (PPSP)

Status: Recruiting
Location: See location...
Intervention Type: Device, Drug
Study Type: Observational
SUMMARY

The purpose of this research is to determine if a PET/MRI scan using FDG can accurately identify the source of chronic pain. Identifying the source of pain may help doctors treat chronic pain more effectively. Approximately 128 participants will be enrolled and can expect to be on study for up to 12 months.

Eligibility
Participation Requirements
Sex: All
Minimum Age: 18
Maximum Age: 85
Healthy Volunteers: t
View:

• 18-85 years old

• Presents with persistent pain with pain score of ≥4 on Numerical Rating Scale \[0:10\] for at least 6 months following joint arthroplasty or arthroscopy.

• Able and willing to provide informed consent

• Willing and able to undergo PET/MRI (arthroplasty and arthroscopy participants) and PET/CT (arthroplasty participants only)

• 18-85 years old

• Asymptomatic (pain score of ≤2 on the NRS) for at least 6 months following joint arthroplasty or arthroscopy.

• Able and willing to provide informed consent

• Willing and able to undergo PET/MRI

Locations
United States
Wisconsin
UW School of Medicine and Public Health
RECRUITING
Madison
Contact Information
Primary
Radiology Studies
Radstudy@uwhealth.org
608-282-8349
Time Frame
Start Date: 2024-11-19
Estimated Completion Date: 2027-06
Participants
Target number of participants: 128
Treatments
Open Surgical Procedure (Arthroplasty)
PPSP subjects who have undergone hip (or knee) joint arthroplasty (i.e., open surgical procedure for joint replacement).~* 6 month post-op scans~* 12 month post-op scans~* 18 month post-op scans
Less Invasive Procedure (Arthroscopy)
PPSP subjects who have undergone hip (or knee) arthroscopy (i.e., less invasive joint surgical procedure involving scopes and lower profile surgical tools)~\- 6 month post-op scans
Asymptomatic: Had Total Joint Replacement (Arthroplasty)
Asymptomatic subjects who have undergone total hip or total knee arthroplasty.~\- single scan during one study visit (up to 3.5 hours)
Asymptomatic: Less Invasive Procedure (Arthroscopy)
Asymptomatic subjects who have undergone hip or knee arthroscopy.~\- single scan during one study visit (up to 3.5 hours)
Related Therapeutic Areas
Sponsors
Collaborators: Arthroscopy Association of North America (AANA), National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS)
Leads: University of Wisconsin, Madison

This content was sourced from clinicaltrials.gov

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